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Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor Initiation

Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor Initiation

June 15, 2025 Category: Blog

Perturbations in stem cell activity and differentiation can lead to developmental defects and cancer.We use an approach involving a Apple CarPlay quantitative model of cell-state transitions in vitro to gain insights into how SLUG/SNAI2, a key developmental transcription factor, modulates mammary epithelial stem cell activity and differentiation in

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Bureaucratic discourse, signature and authorship in John Tzetzes: a comparative perspective

June 15, 2025 Category: Blog

Taking its cue from the work of John Tzetzes (1110-1185 ca), this paper offers a preliminary survey of the role played by bureaucratic and legal training Outdoor End Table in defining autography and authorship in 12th-century Byzantium.By comparing archival practices and authorial signatures, it demonstrates that features belonging to the legal dis

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Building Infrastructure for Preservation and Publication of Earthquake Engineering Research Data

June 15, 2025 Category: Blog

The objective of this paper is to showcase the progress of the earthquake engineering community during a SURVIVAL TOOLS decade-long effort supported by the National Science Foundation in the George E.Brown Jr., Network for Earthquake Engineering Simulation (NEES).During the four years that NEES network operations have been headquartered at Purdue U

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